Abstract# SAT-218 Health-related quality of life in children with hepatitis C viral (HCV) infection treated with sofosbuvir and ribavirin—Z.M. Younossi, et al.
Study Aims and Results: This phase 2 study assessed quality of life outcomes in 50 HCV-positive adolescents treated with sofosbuvir and ribavirin. Treatment success rates were 100% of patients with HCV genotype 2 and 95% with genotype 3.
Conclusions: This study found that adolescents treated with sofosbuvir and ribavirin did not report decreased quality of life during treatment, and had significant improvement in social and school function after responding to HCV treatment.
Editorial Comments: Sadly, there are too few pediatric hepatitis C studies. Another pediatric study highlighted the need to treat children early to prevent progression of liver disease. (THU-286 Chronic hepatitis C in children in the Russian Federation—G.V. Volynets et al.) It’s time to step up pediatric HCV research.
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